108
" Probably you were not quite well, my little dove, when you wrote to me, for a note of real melancholy pervaded your letter. I recognized in it a nature closely akin to my own. I know the feeling only too well. In my life, too, there are days, hours, weeks, aye, and months, in which everything looks black, when I am tormented by the thought that I am forsaken, that no one cares for me. Indeed, my life is of little worth to anyone. Were I to vanish from the face of the earth to-day, it would be no great loss to Russian music, and would certainly cause no one great unhappiness. In short, I live a selfish bachelor’s life. I work for myself alone, and care only for myself. This is certainly very comfortable, although dull, narrow, and lifeless. But that you, who are indispensable to so many whose happiness you make, that you can give way to depression, is more than I can believe. How can you doubt for a moment the love and esteem of those who surround you? How could it be possible not to love you? No, there is no one in the world more dearly loved than you are. As for me, it would be absurd to speak of my love for you. If I care for anyone, it is for you, for your family, for my brothers and our old Dad. I love you all, not because you are my relations, but because you are the best people in the world. "
114
" Concepts of memory tend to reflect the technology of the times. Plato and Aristotle saw memories as thoughts inscribed on wax tablets that could be erased easily and used again. These days, we tend to think of memory as a camera or a video recorder, filming, storing, and recycling the vast troves of data we accumulate throughout our lives. In practice, though, every memory we retain depends upon a chain of chemical interactions that connect millions of neurons to one another. Those neurons never touch; instead, they communicate through tiny gaps, or synapses, that surround each of them. Every neuron has branching filaments, called dendrites, that receive chemical signals from other nerve cells and send the information across the synapse to the body of the next cell. The typical human brain has trillions of these connections. When we learn something, chemicals in the brain strengthen the synapses that connect neurons. Long-term memories, built from new proteins, change those synaptic networks constantly; inevitably, some grow weaker and others, as they absorb new information, grow more powerful. "
― Michael Specter