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21 " The hardcore drug addicts that I treat, are, without exception, people who have had extraordinarily difficult lives. The commonality is childhood abuse. These people all enter life under extremely adverse circumstances. Not only did they not get what they need for healthy development; they actually got negative circumstances of neglect. I don’t have a single female patient in the Downtown Eastside of Vancouver who wasn’t sexually abused, for example, as were many of the men, or abused, neglected and abandoned serially, over and over again. That’s what sets up the brain biology of addiction. In other words, the addiction is related both psychologically, in terms of emotional pain relief, and neurobiological development to early adversity. "
― Gabor Maté
22 " All these years, her sole objective had been to keep still and hope no one would ever know. She had been a mistress of stillness. She had mastered the simulation of peace without a wisp of real peace, like a nun from a silent order who was screaming inside her head, or a yogi racked with pain. How she had managed to fool anyone, let alone everyone, mystified her (how obtuse people were!) and, oddly, made her extraordinarily bitter. Because the price of her gift for evasion was to have no one, not one person, who understood how horrible she felt. All the time. Absolutely all the time. "
― Jean Hanff Korelitz , Admission
23 " Theoretically, I wanted to meditate, but I found actually doing it extraordinarily difficult. As a therapist, I knew that we all want progress, but we resist change. I was a vivid example of this maxim. Figuring out my taxes and going to the dentist were easier than meditating. Even as I told myself meditation was a top priority, I worked to avoid that forty-five minutes alone with my mind. "
― Mary Pipher , Seeking Peace: Chronicles of the Worst Buddhist in the World
24 " Meditation is to find out whether the brain, with all its activities, all its experiences, can be absolutely quiet. Not forced, because the moment you force, there again is duality, the entity that says, 'I would like to have marvellous experiences, therefore I must force my brain to be quiet' - you will never do it. But if you begin to inquire, watch, observe, listen to all the movements of thought, its conditioning, its pursuits, its fears, its pleasures, watch how the brain operates, then you will see that the brain becomes extraordinarily quiet; that quietness is not sleep but is tremendously active and therefore quiet. "
― J. Krishnamurti
25 " What is first seen as a loss is now seen as a gain. For he finds solitude, not in far off, quite places; he creates it out of himself, spreads it around him, wherever he may be, because he loves it and slowly he ripens in this tranquility. For the inner process is beginning to unfold, stillness is extraordinarily important. "
― Janwillem van de Wetering
26 " Sometimes, we wait on God for special things to happen extraordinarily in our lives before we understand that " God is working" . Meanwhile, there are " super-special" things that fill our life barrels in minute drops, but they go unappreciated! "
27 " Jesus, who comes across in the Gospels as extraordinarily strong, begged in the garden, with drops of sweat like blood running down his face, that he might be spared the terrible cup ahead of him, the betrayal and abandonment by his friends, death on the cross. Because Jesus cried out in anguish, we may too. But our fear is less frequent and infinitely less if we are close to the Creator. Jesus, having cried out, then let his fear go, and moved on. "
― Madeleine L'Engle , Glimpses of Grace: Daily Thoughts and Reflections
28 " A ray of sunshine, I bring to the world my passion of guiding others to their point of power by first loving themselves from the inside out. I Am on a never ending journey of self discovery and that has earned me a PHd in life experience I share with you. If your ready to walk the path of happy, I am your partner and together we Can transform your world into something extraordinarily awesome. "
― Lee Pryke
29 " One never knows what fate has in store.” Turning toward Rohan, Amelia discovered he was glancing over her in a slow inventory that spurred her heart into a faster beat. “I don’t believe in fate,” she said. “People are in control of their own destinies.” Rohan smiled. “Everyone, even the gods, are helpless in the hands of fate.” Amelia regarded him skeptically. “Surely you, being employed at a gaming club, know all about probability and odds. Which means you can’t rationally give credence to luck or fate or anything of the sort.” “I know all about probability and odds,” Rohan agreed. “Nevertheless, I believe in luck.” He smiled with a quiet smolder in his eyes that caused her breath to catch. “I believe in magic and mystery, and dreams that reveal the future. And I believe some things are written in the stars … or even in the palm of your hand.” Mesmerized, Amelia was unable to look away from him. He was an extraordinarily beautiful man, his skin as dark as clover honey, his black hair falling over his forehead in a way that made her fingers twitch with the urge to push it back. “Do you believe in fate too?” she asked Merripen. A long hesitation. “I’m a Roma,” he said. Which meant yes. “Good Lord, Merripen. I’ve always thought of you as a sensible man.” Rohan laughed. “It’s only sensible to allow for the possibility, Miss Hathaway. Just because you can’t see or feel something doesn’t mean it can’t exist. "
― Lisa Kleypas , Mine Till Midnight (The Hathaways, #1)
30 " What prince wouldn’t make a country girl a little restless? Those eyes, that mouth, the broad chest, were a royal combination unlike any other. He only held power over her if she let him, though. He brushed his teeth just like every other person. Put on his shoes one foot at a time. Prince Theo was just extraordinarily normal. And she could handle him and her story. Probably. "
― Robin Bielman , Once Upon a Royal Christmas (The Palotays of Montana #2)
31 " What we've done is make the categories of science fiction and fantasy larger, freer, and more inclusive than any other genre of contemporary literature. We have room for everybody, and we are extraordinarily open to genuine experimentation. "
― Orson Scott Card , How to Write Science Fiction & Fantasy
32 " If I have learned one thing from experience, it is this: never underestimate how extraordinarily difficult it is to understand a situation from another person's point of view. "
― Eleanor Catton
33 " He’s such an extraordinarily brilliant person that it would be terrible if he let himself do nothing in the end. "
― Compton Mackenzie , Plashers Mead
34 " One interesting thing is the idea that people have of a kind of science of Aesthetics. I would almost like to talk of what could be meant by Aesthetics.You might think Aesthetics is a science telling us what's beautiful - almost too ridiculous for words. I suppose it ought to include also what sort of coffee tastes well. I see roughly this - there is a realm of utterance of delight, when you taste pleasant food or smell a pleasant smell, etc., then there is a realm of Art which is quite different, though often you may make the same face when you hear a piece of music as when you taste good food. (Though you may cry at something you like very much.)Supposing you meet someone in the street and he tells you he has lost his greatest friend, in a voice extremely expressive of his emotion. You might say: 'It was extraordinarily beautiful, the way he expressed himself.' Supposing you then asked: 'What similarity has my admiring this person with my eating vanilla ice and like it?' To compare them seems almost disgusting. (But you can connect them by intermediate cases.) Suppose someone says 'But this is a quite different kind of delight.' But did you learn two meanings of 'delight'? You use the same word on both occasions. There is some connection between these delights. Although in the first case the emotion of delight would in our judgement hardly count. "
― Ludwig Wittgenstein , Lectures and Conversations on Aesthetics, Psychology and Religious Belief
35 " I'm not important, having a child is not an amazing feat, and my child, while extraordinarily important to and beloved by her parents, is not particularly special in the scheme of things. "
36 " The shadow that comes with postmodernism is a profound self-involvement. We lose all perspective on the collective endeavors that have made the extraordinarily lives we live possible. "
― James M. Fallows
37 " Somatic hypermutation gives rise to B cells bearing mutant immunoglobulin molecules on their surface. Some of these mutant immunoglobulins have substitutions in the antigen-binding site that increase its affinity for the antigen. B cells bearing these mutant high-affinity immunoglobulin receptors compete most effectively for binding to antigen and are preferentially selected to mature into antibody-secreting plasma cells. The mutant antibodies that emerge from the selection do not have a random distribution of amino-acid substitutions. The changes are concentrated at positions in the heavy-chain and light-chain CDR loops that form the antigen-binding site and directly contact antigen. As the adaptive immune response to infection proceeds, antibodies of progressively higher affinity for the infecting pathogen are produced – a phenomenon called affinity maturation. Affinity maturation is a process of evolution in which variant immunoglobulins generated in a random manner are subjected to selection for improved binding to a pathogen. It achieves in a few days what would require thousands, if not millions, of years of classical Darwinian evolution in a conventional gene. This capacity for extraordinarily rapid evolution in pathogen-binding immunoglobulins is a major factor in allowing the human immune system to keep up with the generally faster-evolving pathogens. "
― , The Immune System
38 " When one ponders on the tremendous journey of evolution over the past three billion years or so, the prodigious wealth of structures it has engendered, and the extraordinarily effective teleonomic performances of living beings from bacteria to man, one may well find oneself beginning to doubt again whether all this could conceivably be the product of an enormous lottery presided over by natural selection, blindly picking the rare winners from among numbers drawn at random. [Nevertheless,] a detailed review of the accumulated modern evidence [shows] that this conception alone is compatible with the facts. "
― Jacques Monod , Chance and Necessity: An Essay on the Natural Philosophy of Modern Biology
39 " An extraordinarily rare ability is in your possession. Hone the skills so you effectively utilize your gift. As we speak and as you wile away your time, the aswang is preparing to strike again. Lives are at stake! "
40 " Beauty works perfect miracles. All inner shortcomings in a beauty, instead of causing repugnance, become somehow extraordinarily attractive; vice itself breathes comeliness in them; but if it were to disappear, then a woman would have to be twenty times more intelligent than a man in order to inspire, if not love, at least respect. "
― Nikolai Gogol , The Collected Tales of Nikolai Gogol