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The Drunkard's Walk: How Randomness Rules Our Lives QUOTES

1 " Perception requires imagination because the data people encounter in their lives are never complete and always equivocal. For example, most people consider that the greatest evidence of an event one can obtain is to see it with their own eyes, and in a court of law little is held in more esteem than eyewitness testimony. Yet if you asked to display for a court a video of the same quality as the unprocessed data catptured on the retina of a human eye, the judge might wonder what you were tryig to put over. For one thing, the view will have a blind spot where the optic nerve attaches to the retina. Moreover, the only part of our field of vision with good resolution is a narrow area of about 1 degree of visual angle around the retina’s center, an area the width of our thumb as it looks when held at arm’s length. Outside that region, resolution drops off sharply. To compensate, we constantly move our eyes to bring the sharper region to bear on different portions of the scene we wish to observe. And so the pattern of raw data sent to the brain is a shaky, badly pixilated picture with a hole in it. Fortunately the brain processes the data, combining input from both eyes, filling in gaps on the assumption that the visual properties of neighboring locations are similar and interpolating. The result - at least until age, injury, disease, or an excess of mai tais takes its toll - is a happy human being suffering from the compelling illusion that his or her vision is sharp and clear.

We also use our imagination and take shortcuts to fill gaps in patterns of nonvisual data. As with visual input, we draw conclusions and make judgments based on uncertain and incomplete information, and we conclude, when we are done analyzing the patterns, that out “picture” is clear and accurate. But is it? "

Leonard Mlodinow , The Drunkard's Walk: How Randomness Rules Our Lives

14 " To understand my doctor’s error, let’s employ Bayes’s method. The first step is to define the sample space. We could include everyone who has ever taken an HIV test, but we’ll get a more accurate result if we employ a bit of additional relevant information about me and consider only heterosexual non-IV-drug-abusing white male Americans who have taken the test. (We’ll see later what kind of difference this makes.) Now that we know whom to include in the sample space, let’s classify the members of the space. Instead of boy and girl, here the relevant classes are those who tested positive and are HIV-positive (true positives), those who tested positive but are not positive (false positives), those who tested negative and are HIV-negative (true negatives), and those who tested negative but are HIV-positive (false negatives). Finally, we ask, how many people are there in each of these classes? Suppose we consider an initial population of 10,000. We can estimate, employing statistics from the Centers for Disease Control and Prevention, that in 1989 about 1 in those 10,000 heterosexual non-IV-drug-abusing white male Americans who got tested were infected with HIV.6 Assuming that the false-negative rate is near 0, that means that about 1 person out of every 10,000 will test positive due to the presence of the infection. In addition, since the rate of false positives is, as my doctor had quoted, 1 in 1,000, there will be about 10 others who are not infected with HIV but will test positive anyway. The other 9,989 of the 10,000 men in the sample space will test negative. Now let’s prune the sample space to include only those who tested positive. We end up with 10 people who are false positives and 1 true positive. In other words, only 1 in 11 people who test positive are really infected with HIV. "

Leonard Mlodinow , The Drunkard's Walk: How Randomness Rules Our Lives