QUOTE : Bereavement is useful; full-blown depression is not. William Styron renders an eloquent description of “the many dreadful manifestations of the disease,” among them self-hatred, a sense of worthlessness, a “dank joylessness” with “gloom crowding in on me, a sense of dread and alienation and, above all, a stifling anxiety.”14 Then there are the intellectual marks: “confusion, failure of mental focus and lapse of memories,” and, at a later stage, his mind “dominated by anarchic distortions,” and “a sense that my thought processes were engulfed by a toxic and unnameable tide that obliterated any enjoyable response to the living world.” There are the physical effects: sleeplessness, feeling as listless as a zombie, “a kind of numbness, an enervation, but more particularly an odd fragility,” along with a “fidgety restlessness.” Then there is the loss of pleasure: “Food, like everything else within the scope of sensation, was utterly without savor.” Finally, there was the vanishing of hope as the “gray drizzle of horror” took on a despair so palpable it was like physical pain, a pain so unendurable that suicide seemed a solution. In such major depression, life is paralyzed; no new beginnings emerge. The very symptoms of depression bespeak a life on hold. For