" With behavior therapy, there is also a change in the function of the cingulate gyrus, that part of the cortex that is responsible for the feeling that something catastrophic is going to happen if you don’t act on your compulsions. Before treatment, the cingulate gyrus is tightly locked to the orbital cortex, which is probably the reason why obsessive thoughts and urges are accompanied by such terrible feelings of dread. This is one of the major problems in Brain Lock. After the person follows the Four Steps, the orbital cortex and cingulate gyrus uncouple and start to work freely again, and the fear and dread markedly decrease. "

― Jeffrey M. Schwartz , Brain Lock: Free Yourself from Obsessive-Compulsive Behavior