" This half century of research unequivocally supported the alternative hypothesis of obesity. It established that the relevant energy balance isn’t between the calories we consume and the calories we expend, but between the calories—in the form of free fatty acids, glucose, and glycerol—passing in and out of the fat cells. If more and more fatty acids are fixed in the fat tissue than are released from it, obesity will result. "

― Gary Taubes , Good Calories, Bad Calories: Challenging the Conventional Wisdom on Diet, Weight Control, and Disease