" Allinson’s chain of cause and effect from white bread to constipation to chronic disease was given credibility in the late 1920s by the innovative and eccentric Scottish surgeon Sir Arbuthnot Lane in a book entitled The Prevention of the Diseases Peculiar to Civilization. The hypothesis would hold a tight grasp on a school of British medical researchers for decades to come. "

― Gary Taubes , Good Calories, Bad Calories: Challenging the Conventional Wisdom on Diet, Weight Control, and Disease