" There exists no Kantian radically autonomous person, with absolute freedom and a transcendent reason that correctly dictates what is and isn't moral. Reason, arising from the body, doesn't transcend the body. What universal aspects of reason there are arise from the commonalities of our bodies and brains and the environments we inhabit. The existence of these universals does not imply that reason transcends the body. Moreover, since conceptual systems vary significantly, reason is not entirely universal.

Since reason is shaped by the body, it is not radically free, because the possible human conceptual systems and the possible forms of reason are limited. In addition, once we have learned a conceptual system, it is neurally instantiated in our brains and we are not free to think just anything. Hence, we have no absolute freedom in Kant's sense, no full autonomy. There is no a priori, purely philosophical basis for a universal concept of morality and no transcendent, universal pure reason that could give rise to universal moral laws. "

― George Lakoff , Philosophy in the Flesh: The Embodied Mind and its Challenge to Western Thought