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1 " Too many of our preferences reflect nasty behaviours and states of mind that were genetically adaptive in the ancestral environment. Instead, wouldn't it be better if we rewrote our own corrupt code? "
― David Pearce
2 " The Hedonistic Imperative outlines how genetic engineering and nanotechnology will abolish suffering in all sentient life. This project is ambitious but technically feasible. It is also instrumentally rational and ethically mandatory. The metabolic pathways of pain and malaise evolved only because they once served the fitness of our genes. They will be replaced by a different sort of neural architecture. States of sublime well-being are destined to become the genetically pre-programmed norm of mental health. The world's last aversive experience will be a precisely dateable event. "
3 " I predict we will abolish suffering throughout the living world. Our descendants will be animated by gradients of genetically pre-programmed well-being that are orders of magnitude richer than today's peak experiences. "
― David Pearce , The Hedonistic Imperative
4 " It's not that there are no differences between human and non-human animals, any more than there are no differences between black people and white people, freeborn citizens and slaves, men and women, Jews and gentiles, gays or heterosexuals. The question is rather: are they morally relevant differences? This matters because morally catastrophic consequences can ensue when we latch on to a real but morally irrelevant difference between sentient beings. "
5 " The necessity of the experimental method in scientific investigation of the third-person properties of matter and energy has been recognised since Galileo. The intellectual achievements of physical science, as traditionally conceived, are widely celebrated. By contrast, experimental investigation of the great majority of intrinsic, first-person properties of matter and energy is stigmatised and even criminalised. States of sentience as different as waking from dreaming consciousness are outlawed. Instead of Nobel laureates, research grants and lavish institutional funding, an empirically-driven exploration of the first-person properties of matter and energy plays out mainly within the scientific counterculture. "
― David Pearce ,
6 " A lot of people recoil from the word "drugs" - which is understandable given today's noxious street drugs and their uninspiring medical counterparts. Yet even academics and intellectuals in our society typically take the prototypical dumb drug, ethyl alcohol. If it's socially acceptable to take a drug that makes you temporarily happy and stupid, then why not rationally design drugs to make people perpetually happier and smarter? Presumably, in order to limit abuse-potential, one would want any ideal pleasure drug to be akin - in one limited but important sense - to nicotine, where the smoker's brain finely calibrates its optimal level: there is no uncontrolled dose-escalation. "
7 " It is easy to romanticise, say, tigers or lions and cats. We admire their magnificent beauty, strength and agility. But we would regard their notional human counterparts as wanton psychopaths of the worst kind. "
8 " [...] both natural selection and the historical record offer powerful reasons for doubting the trustworthiness of our naive moral intuitions. So the possibility that human civilisation might be founded upon some monstrous evil should be taken seriously - even if the possibility seems transparently absurd at the time. "
9 " [...] there is no need to pay homage to the product of selfish genes - as though self-replicating DNA from the old Darwinian era were some sort of secular equivalent to Providence. "
10 " For better or worse, humans or our descendants will be responsible for life on Earth for the indefinite future. Despite the initially daunting technical challenges, the biggest obstacle to compassionate stewardship of the world's free-living nonhuman animal population is not technical or even financial but ideological. "
11 " [...] true hedonic engineering, as distinct from mindless hedonism or reckless personal experimentation, can be profoundly good for our character. Character-building technologies can benefit utilitarians and non-utilitarians alike. Potentially, we can use a convergence of biotech, nanorobotics and information technology to gain control over our emotions and become better (post-)human beings, to cultivate the virtues, strength of character, decency, to become kinder, friendlier, more compassionate: to become the type of (post)human beings that we might aspire to be, but aren't, and biologically couldn't be, with the neural machinery of unenriched minds. Given our Darwinian biology, too many forms of admirable behaviour simply aren't rewarding enough for us to practise them consistently: our second-order desires to live better lives as better people are often feeble echoes of our baser passions. "
12 " The junkie derives his opioid supply exogenously; while the release of endogenous opioids in the rest of us is triggered, and not always very reliably either, by stimuli such as food, sex, exercise and social interaction. We're all still seeking the same core states of psycho-chemical well-being under one description or other. "
