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1 " They never look very big on the table, the bodies. It's built to accommodate the largest frames, there's that. And they're naked. But it's something else. That parcel of the being called the soul-weighing twenty-one grams, according to the experiments of the American doctor Duncan MacDougall-takes up a surprising amount of space, like aloud voice. In its absence, the body seems to shrink "
― Yann Martel , The High Mountains of Portugal
2 " [At the beginning of modern science], a light dawned on all those who study nature. They comprehended that reason has insight only into what it itself produces according to its own design; that it must take the lead with principles for its judgments according to constant laws and compel nature to answer its questions, rather than letting nature guide its movements by keeping reason, as it were, in leading-strings; for otherwise accidental observations, made according to no previously designed plan, can never connect up into a necessary law, which is yet what reason seeks and requires. Reason, in order to be taught by nature, must approach nature with its principles in one hand, according to which alone the agreement among appearances can count as laws, and, in the other hand, the experiments thought in accordance with these principles - yet in order to be instructed by nature not like a pupil, who has recited to him whatever the teacher wants to say, but like an appointed judge who compels witnesses to answer the questions he puts to them. Thus even physics owes the advantageous revolution in its way of thinking to the inspiration that what reason would not be able to know of itself and has to learn from nature, it has to seek in the latter (though not merely ascribe to it) in accordance with what reason itself puts into nature. This is how natural science was first brought to the secure course of a science after groping about for so many centuries. "
― Immanuel Kant , Critique of Pure Reason
3 " I don't know if you realize this, but there are some researchers - doctors - who are giving this kind of drug to volunteers, to see what the effects are, and they're doing it the proper scientific way, in clean white hospital rooms, away from trees and flowers and the wind, and they're surprised at how many of the experiments turn sour. They've never taken any sort of psychedelic themselves, needless to say. Their volunteers - they're called 'subjects,' of course - are given mescaline or LSD and they're all opened up to their surroundings, very sensitive to color and light and other people's emotions, and what are they given to react to? Metal bed-frames and plaster walls, and an occasional white coat carrying a clipboard. Sterility. Most of them say afterward that they'll never do it again. "
― Alexander Shulgin , Pihkal: A Chemical Love Story
4 " Very little useful science got done in the space station. NASA never did the experiments needed to develop the technologies required for a genuine interplanetary expedition: centrifugal gravity to avoid bodily harm and a truly closed biosphere. "
5 " Whether it's the experiments on 'MythBusters' or my earlier work in special effects for movies, I've regularly had to do things that were never done before, from designing complex motion-control rigs to figuring out how to animate chocolate. "