1
" Thus with the question of the Being of truth and the necessity of presupposing it, just as with the question of the essence of knowledge, an 'ideal subject' has generally been posited. The motive for this, whether explicit or tacit, lies in the requirement that philosophy should have the '*a priori*' as its theme, rather than 'empirical facts' as such. There is some justification for this requirement, though it still needs to be grounded ontologically. Yet is this requirement satisfied by positing an 'ideal subject'? Is not such a subject *a fanciful idealization*? With such a conception have we not missed precisely the *a priori* character of that merely 'factual' subject, Dasein? Is it not an attribute of the *a priori* character of the factical subject (that is, an attribute of Dasein's facticity) that it is in the truth and in untruth equiprimordially?The ideas of a 'pure " I" ' and of a 'consciousness in general' are so far from including the *a priori* character of 'actual' subjectivity that the ontological characters of Dasein's facticity and its state of being are either passed over or not seen at all. Rejection of a 'consciousness in general' does not signify that the *a priori* is negated, any more than the positing of an idealized subject guarantees that Dasein has an *a priori* character grounded upon fact.Both the contention that there are 'eternal truths' and the jumbling together of Dasein's phenomenally grounded 'ideality' with an idealized absolute subject, belong to those residues of Christian theology within philosophical problematics which have not as yet been radically extruded.The Being of truth is connected primordially with Dasein. And only because Dasein is as constituted by disclosedness (that is, by understanding), can anything like Being be understood; only so is it possible to understand Being." ―from_Being and Time_. Translated by John Macquarrie & Edward Robinson, p. 272 "
2
" If you imagine the 4,500-bilion-odd years of Earth's history compressed into a normal earthly day, then life begins very early, about 4 A.M., with the rise of the first simple, single-celled organisms, but then advances no further for the next sixteen hours. Not until almost 8:30 in the evening, with the day five-sixths over, has Earth anything to show the universe but a restless skin of microbes. Then, finally, the first sea plants appear, followed twenty minutes later by the first jellyfish and the enigmatic Ediacaran fauna first seen by Reginald Sprigg in Australia. At 9:04 P.M. trilobites swim onto the scene, followed more or less immediately by the shapely creatures of the Burgess Shale. Just before 10 P.M. plants begin to pop up on the land. Soon after, with less than two hours left in the day, the first land creatures follow.
Thanks to ten minutes or so of balmy weather, by 10:24 the Earth is covered in the great carboniferous forests whose residues give us all our coal, and the first winged insects are evident. Dinosaurs plod onto the scene just before 11 P.M. and hold sway for about three-quarters of an hour. At twenty-one minutes to midnight they vanish and the age of mammals begins. Humans emerge one minute and seventeen seconds before midnight. The whole of our recorded history, on this scale, would be no more than a few seconds, a single human lifetime barely an instant. Throughout this greatly speeded-up day continents slide about and bang together at a clip that seems positively reckless. Mountains rise and melt away, ocean basins come and go, ice sheets advance and withdraw. And throughout the whole, about three times every minute, somewhere on the planet there is a flash-bulb pop of light marking the impact of a Manson-sized meteor or one even larger. It's a wonder that anything at all can survive in such a pummeled and unsettled environment. In fact, not many things do for long. "
― Bill Bryson , A Short History of Nearly Everything
6
" In describing a protein it is now common to distinguish the primary, secondary and tertiary structures. The primary structure is simply the order, or sequence, of the amino-acid residues along the polypeptide chains. This was first determined by [Frederick] Sanger using chemical techniques for the protein insulin, and has since been elucidated for a number of peptides and, in part, for one or two other small proteins. The secondary structure is the type of folding, coiling or puckering adopted by the polypeptide chain: the a-helix structure and the pleated sheet are examples. Secondary structure has been assigned in broad outline to a number of librous proteins such as silk, keratin and collagen; but we are ignorant of the nature of the secondary structure of any globular protein. True, there is suggestive evidence, though as yet no proof, that a-helices occur in globular proteins, to an extent which is difficult to gauge quantitatively in any particular case. The tertiary structure is the way in which the folded or coiled polypeptide chains are disposed to form the protein molecule as a three-dimensional object, in space. The chemical and physical properties of a protein cannot be fully interpreted until all three levels of structure are understood, for these properties depend on the spatial relationships between the amino-acids, and these in turn depend on the tertiary and secondary structures as much as on the primary. Only X-ray diffraction methods seem capable, even in principle, of unravelling the tertiary and secondary structures.
[Co-author with G. Bodo, H. M. Dintzis, R. G. Parrish, H. Wyckoff, and D. C. Phillips] "
― John Kendrew
