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1 " Playing nice" comes naturally when our neuroception detects safety and promotes physiological states that support social behavior. However, pro-social behavior will not occur when our neuroception misreads the environmental cues and triggers physiological states that support defensive strategies. After all, " playing nice" is not appropriate or adaptive behavior in dangerous or life-threatening situations. In these situations, humans - like other mammals - react with more primitive neurobiological defense systems. To create relationships, humans must subdue these defensive reactions to engage, attach, and form lasting social bonds. Humans have adaptive neurobehavioral systems for both pro-social and defensive behaviors. "
2 " The prevarication and white lies which a mind that keeps itself ambitiously pure is as uneasy under as a great artist under the false touches that no eye detects but his own, are worn as lightly as mere trimming when once the actions have become a lie. "
― George Eliot , Silas Marner
3 " TP53 seems to encode the greater good, like a suicide pill in the mouth of a soldier that dissolves only when it detects evidence that he is about to mutiny. "
― Matt Ridley , Genome: the Autobiography of a Species in 23 Chapters
4 " The Artist is he who detects and applies the law from observation of the works of Genius, whether of man or Nature. The Artisan is he who merely applies the rules which others have detected. "
