" In fact, none of the papers published in the JME over the entire course of its life as a journal has ever proposed a detailed model by which a complex biochemical system might have been produced in a gradual, step-by-step Darwinian fashion. Although many scientists ask how sequences can change or how chemicals necessary for life might be produced in the absence of cells, no one has ever asked in the pages of JME such questions as the following: How did the photosynthetic reaction center develop? How did intramolecular transport start? . . . The very fact that none of these problems is even addressed, let alone solved, is a very strong indication that Darwinism is an inadequate framework for understanding the origin of complex biochemical systems. "

― Michael J. Behe , Darwin's Black Box: The Biochemical Challenge to Evolution