" The fever” was (as it usually is in Manchester) of a low, putrid, typhoid kind; brought on by miserable living, filthy neighbourhood, and great depression of mind and body. It is virulent, malignant, and highly infectious. But the poor are fatalists with regard to infection! and well for them it is so, for in their crowded dwellings no invalid can be isolated. "

― Elizabeth Gaskell , The Complete Elizabeth Gaskell Collection