" Given the NIH's lack of record keeping, it was impossible to say exactly how underrepresented women were, but the public learned that women had been left out of many of the largest, most important clinic studies conducted in the last couple of decades. The Baltimore Longitudinal Study of Aging, which began in 1958 and purported to explore 'normal human aging,' didn't enroll any women for the first twenty years it ran. The Physicians' Health Study, which had recently concluded that taking a daily aspirin may reduce the risk of heart disease? Conducted in 22,071 men and zero women. The 1982 Multiple Risk Factor Intervention Trial - known, aptly enough, as MRFIT - which looked at whether dietary change and exercise could help prevent heart disease: just 13,000 men. "
― Maya Dusenbery , Doing Harm: The Truth About How Bad Medicine and Lazy Science Leave Women Dismissed, Misdiagnosed, and Sick