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" When fructose is metabolized in the liver, for instance, it accelerates the breakdown of a molecule called ATP, which is the primary source of energy for cellular reactions and is loaded with purines. (“ATP” stands for “adenosine triphosphate”; adenosine is a form of adenine, a purine.) This in turn increases the formation of uric acid. Alcohol raises uric acid levels through the same mechanism (although beer also has purines in it). The effect of fructose on ATP also works to stimulate the synthesis of purines, and the metabolism of fructose leads to the production of lactic acid, which reduces the excretion of uric acid by the kidney and thereby raises uric acid concentrations indirectly. "

Gary Taubes , The Case Against Sugar


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Gary Taubes quote : When fructose is metabolized in the liver, for instance, it accelerates the breakdown of a molecule called ATP, which is the primary source of energy for cellular reactions and is loaded with purines. (“ATP” stands for “adenosine triphosphate”; adenosine is a form of adenine, a purine.) This in turn increases the formation of uric acid. Alcohol raises uric acid levels through the same mechanism (although beer also has purines in it). The effect of fructose on ATP also works to stimulate the synthesis of purines, and the metabolism of fructose leads to the production of lactic acid, which reduces the excretion of uric acid by the kidney and thereby raises uric acid concentrations indirectly.