" Another set of mismatch diseases that can be caused by farming diets are nutrient deficiencies. Many of the molecules that make grains like rice and wheat nutritious, healthful, and sustaining are the oils, vitamins, and minerals present in the outer bran and germ layers that surround the mostly starchy central part of the seed. Unfortunately, these nutrient-rich parts of the plant also spoil rapidly. Since farmers must store staple foods for months or years, they eventually figured out how to refine cereals by removing the outer layers, transforming rice or wheat from “brown” into “white.” These technologies were not available to the earliest farmers, but once refining became common the process removed a large percentage of the plant’s nutritional value. For instance, a cup of brown and white rice have nearly the same caloric content, but the brown rice has three to six times as much B vitamins, plus other minerals and nutrients such as vitamin E, magnesium, potassium, and phosphorus. Refined "

― Daniel E. Lieberman , The Story of the Human Body: Evolution, Health, and Disease