" On the other hand, I am not very sceptical,—a frame of mind which I believe to be injurious to the progress of science. A good deal of scepticism in a scientific man is advisable to avoid much loss of time, but I have met with not a few men, who, I feel sure, have often thus been deterred from experiment or observations, which would have proved directly or indirectly serviceable. "

― Charles Darwin , The Autobiography of Charles Darwin, 1809–82