" Aggression and depression sound like two different, even polarized phenomena, but they’re not. Depression is aggression turned inward, directed against the self, or the imagined, threatening self. A seriously depressed person may look anesthetized to an observer, but the depressed person is never anesthetized to herself. She may wish to be, and she may seek to be with chemical aid, but she cannot truly placate her sneering, jabbering, nested aggressor. "
― Natalie Angier , Woman: An Intimate Geography